Clinical Biostatistics (CLB)

To enable students to use correctly statistical methods of particular relevance to evidence-based health care and to advise clinicians on the application of these methods and interpretation of the results.


Dr Michael Waller, School of Public Health, University of Queensland

Dr Michael Waller University of Queensland, School of Public Health Semester 1
General outline


Epidemiology, Mathematical Background for Biostatistics, Probability and Distribution Theory, Principles of Statistical Inference, Design of Randomised Controlled Trials


Linear Models

Time commitment

8-12 hours total study time per week

Semester availability

Semester 1


Assignments 100% (3 written assignments worth 30%, 35%, 35%)

Prescribed Texts

References will be listed in the unit Study Guide

Special Computer Requirements

Stata or R statistical software


Clinical trials (equivalence trials, cross-over trials); Clinical agreement (BlandAltman methods, kappa statistics, intraclass correlation); Statistical process control (special and common causes of variation; quality control charts); Diagnostic tests (sensitivity, specificity, ROC curves); Meta-analysis (systematic reviews, assessing heterogeneity, publication bias, estimating effects from randomised controlled trials, diagnostic tests and observational studies).

Special Computer Requirements

Course notes, assignment material and interaction facilities available online